Aridhia DRE - Trusted Research Environment
Thought Leadership & Research

Papers & Publications

We feel it’s important to maintain a high level of thought leadership in our field, providing insight and guidance to the health science domain in order to better serve the interests of our customers and, ultimately, patients.

Paper DARE UK TREvolution Final Report

Aridhia's DARE UK TREvolution final report: federated TRE workspace integration, GA4GH Task Execution Service implementation, and Federated Node development.

DOI: 10.5281/zenodo.19206117

Paper Assessing the Aridhia DRE against the SATRE specification for 2026

This paper scores the Aridhia DRE against the four sections of the SATRE specification for 2026.

Paper DARE UK TREvoultion Interim Report

This interim report details initial work carried out by Aridhia under the DARE UK TREvolution project.

DOI: 10.5281/zenodo.17573488

Paper Delivering Regulatory Impact from Consortium-Based Projects

How consortium-based drug development programmes achieve regulatory milestones. Lessons from C-Path, IHI, and the RDCA-DAP platform built on the Aridhia DRE.

DOI: 10.1111/cts.70215

Paper The GOSH-Aridhia DRE Partnership: Creating a Secure and Scalable Data Platform to Support Research and Clinical Advancements

How GOSH and Aridhia partnered in 2017 to build a state-of-the-art Digital Research Environment, now supporting 400+ active research and clinical projects.

Paper Unlocking the Mysteries of Rare Disease Drug Development: A Beginner’s Guide for Clinical Pharmacologists

A beginner's guide for clinical pharmacologists entering rare disease drug development. Published in Clinical and Translational Science, 2025

DOI: 10.1111/cts.70215

Paper Innovations and Best Practices for Therapeutic Development in Pediatric Rare Diseases: A Model-Informed Drug Development Perspective

MIDD innovations for paediatric rare disease drug development, addressing small populations and patient heterogeneity. Published Clin Pharmacol Ther, 2025

DOI: 10.1002/cpt.3683

Paper Crowdsourcing Proposal Supporting Patient Engagement in Parkinson’s Disease: A Digital Research Environment-Enabled Patient Swarm Approach to Develop QSP Models

How a DRE-enabled patient swarm approach incorporates the patient voice into collaborative QSP model development for Parkinson's disease across academic centres

DOI: 10.1002/jcph.70028

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