Aridhia DRE - Trusted Research Environment
Thought Leadership & Research

Papers & Publications

We feel it’s important to maintain a high level of thought leadership in our field, providing insight and guidance to the health science domain in order to better serve the interests of our customers and, ultimately, patients.

Paper Data Federation in a Trusted Research Environment

This whitepaper covers the concept of data federation within a trusted research environment by using the example of Aridhia’s work with the PHEMS consortium.

Paper Consideration of the Root Causes in Candidate Attrition During Oncology Drug Development

Oncology candidates fail at twice the rate of other therapeutic areas. This paper examines root causes of attrition from first-in-human through to registration.

DOI: 10.1002/cpdd.1464

Paper Artificial Intelligence Opportunities to Guide Precision Dosing Strategies

How AI guides precision dosing, therapeutic drug monitoring, biomarker integration and individualised pharmacotherapy. Published J Pediatr Pharmacol Ther, 2024.

DOI: 10.5863/1551-6776-29.4.434

Paper A modern curriculum for training scientists in model-informed drug development: Progress report on FDA grant to train regulatory scientists

C-Path and partners report progress on an FDA-funded MIDD e-learning curriculum for regulatory scientists — published in Clinical Pharmacology & Therapeutics.

DOI: 10.1002/cpt.3039

Paper Implementing precision medicine with the Liver Cancer Collaborative

How the Liver Cancer Collaborative implemented precision medicine using the Aridhia DRE. A blueprint for governed, collaborative cancer research delivery.

Paper Bringing platform trials closer to reality by enabling with digital research environment (DRE) connectivity

How DRE connectivity enables platform trials. Shared infrastructure, governed multi-site data access, and adaptive trial design at scale.

DOI: 10.1016/j.cct.2024.107559

Paper Assessing the Aridhia DRE against the SATRE specification

This paper scores the DRE against the four sections of the SATRE specification and summarises some of the features that we believe contribute toward that score.

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